|
Thyrotoxic myopathy (TM) is a neuromuscular disorder that develops due to the overproduction of the thyroid hormone thyroxine. Also known as hyperthyroid myopathy, TM is one of many myopathies that lead to muscle weakness and muscle tissue breakdown. Evidence indicates the onset may be caused by hyperthyroidism.〔Kazakov, V.M., Terminal Intramuscular Motor Innervation and Motor End-Plates in Thyrotoxic Myopathy 2:343-349 (1992)〕 There are two known causes of hyperthyroidism that lead to development thyrotoxic myopathy including a multinodular goiter and Graves' disease. Physical symptoms of TM may include muscle weakness, the breakdown of muscle tissue, fatigue, and heat intolerance.〔Quinn EL, Worcester RL, Chronic thyrotoxic myopathy - report of a case. ''Journal of Clinical Endocrinology'' 11:1564-1571.1951.〕 Physical acts such as lifting objects and climbing stairs may become increasingly difficult.〔Horak HA, Pourmand R Endocrine myopathies. ''Neurologic Clinics'' 18:203-+ 2000.〕 If untreated, TM can be an extremely debilitating disorder that can, in extreme rare cases, lead to death. If diagnosed and treated properly the effects can be controlled and in most cases reversed leaving no lasting effects. ==Symptoms== Physical symptoms may include: * Muscle weakness * Degeneration of muscle tissue * Fatigue * Heat intolerance 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Thyrotoxic myopathy」の詳細全文を読む スポンサード リンク
|